Ready to take your photos to the next level? Let’s dive right in, starting with the most important question of all:
The aperture is the opening in the camera lens. A larger hole allows more light to hit the sensor, lightening your photos. A smaller hole allows less light to hit the sensor, darkening your photos.
And by adjusting the aperture setting on your camera, you can adjust the size of the aperture (and, in turn, affect a photo’s brightness).
Aperture is measured in terms of f-stops, also known as f-numbers. Like this: f/2.8, f/4, f/5.6, f/8, f/22, etc.
Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been able to come off insulin altogether within a year, raising the prospect of a life without regular injections.
The new data from Vertex’s phase 1/2 trial of VX-880, presented at the American Diabetes Association (ADA) annual congress in Florida, suggest that the therapy can restore the physiological activity of the insulin-producing islet cells of the pancreas and restore glucose control.
The study enrolled 17 people with type 1 diabetes and impaired hypoglycemia awareness, meaning they find it hard to spot the telltale signs of declining blood sugar levels and are at increased risk of severe hypoglycemic events (SHEs) that can cause confusion, coma, seizures, cardiovascular events, and even death.
The new data came from a group of 12 treated with the full dose of VX-880 given as a single infusion, three of whom had been followed up for at least 12 months and so could be evaluated for efficacy.